February 2024
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Paget’s-Disease

Not a cancer. Paget’s disease is the most common bone disorder characterised by irregular thickening and softening of the bones. The disease is more common after the age of 40, and is frequent in those of European descent but rare in Asians. These is an association with this (non malignant) disease and bone cancer, up to 10% of those with Paget’s disease will have a ‘sarcomatous transformation’ of affected bones giving rise to bone sarcoma. This may be osteosarcoma, fibrosarcoma, chondrosarcoma, or other bone sarcomas. Compare with: Osteogenic Sarcoma

 

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